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  • Methocarbamol is given by mouth or injection and is used on and off label to treat muscle spasms due to injury, inflammation, or certain toxicities. Give as directed by your veterinarian. The most common side effect includes sleepiness. Do not use methocarbamol in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.

  • Methylprednisolone is given by mouth or injection and is used on and off label in dogs, cats, and horses to treat inflammatory, immune-mediated, and hormonal conditions. Common side effects include increased drinking, urination, and appetite, dull/dry haircoat, and/or weight gain.

  • Methylsulfonylmethane is given by mouth and is used over the counter and off label to treat inflammatory conditions such as arthritis. Give as directed by your veterinarian. Side effects are uncommon but may include stomach upset, restlessness, or tiredness. Do not use in pets that are allergic to it or that are pregnant or nursing. If a negative reaction occurs, please call your veterinary office.

  • Metoclopramide is given by mouth or injection and is used off-label to treat gastrointestinal motility disorders, nausea, and vomiting in dogs, cats, and other animals. Give as directed. Side effects are uncommon but may include restlessness, hyperactivity, muscle twitches, drowsiness, and increased urination. Do not use in pets with intestinal blockage or bleeding, pseudopregnancy, pheochromocytoma, or a history of seizures or head trauma. If a negative reaction occurs, contact your veterinarian.

  • Metronidazole is given by mouth or injection and is used off-label to treat certain anaerobic bacterial and protozoal infections and gastrointestinal conditions in dogs, cats, and other animals. Give as directed. Side effects may include nausea, vomiting, diarrhea, regurgitation, decreased appetite, tiredness, and drooling. Do not use in pets that are allergic to it, are debilitated, or are pregnant or nursing. If a negative reaction occurs, contact your veterinarian.

  • Miconazole otic is an antifungal used in the treatment of external ear infections (otitis externa) caused by fungal organisms in cats, dogs, and other animals. It may be specially compounded and/or combined into a formulation with other medications. Miconazole otic comes in ointment or liquid drop suspension forms that may be specially compounded.

  • Midazolam is a benzodiazepine used for its sedative, anti-anxiety, and muscle relaxant properties. It is primarily used as a sedative before surgery and to stop seizures. It is used “off label” or “extra label” in animals. This medication is a controlled substance primarily given via injection by your veterinary team, though it may be prescribed to your pet for intranasal or intrarectal administration at home.

  • Silymarin is an over-the-counter nutritional supplement that is used off-label and is given by mouth to treat liver and cancer conditions. Give as directed. Side effects are uncommon but may include vomiting or diarrhea. Do not use it in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.

  • Mites and lice can cause trouble for guinea pigs. Some mites may cause no clinical signs, while others can cause extreme signs, including itchiness, crusty skin, hair loss, and secondary bacterial skin infection. This article summarizes diagnosis and treatment.

  • Mites affecting pet hedgehogs, often called quill mites, are fairly common. Initially, an affected hedgehog may become itchy but if mites are left untreated, the clinical signs can become severe.